Product Name :
Praliciguat
Description:
Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM.
CAS:
1628730-49-3
Molecular Weight:
534.36
Formula:
C21H14F8N6O2
Chemical Name:
1,1,1-trifluoro-3-[(5-fluoro-2-{1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)-1H-pyrazol-3-yl}pyrimidin-4-yl)amino]-2-(trifluoromethyl)propan-2-ol
Smiles :
OC(CNC1=NC(=NC=C1F)C1C=C(C2C=CON=2)N(CC2=CC=CC=C2F)N=1)(C(F)(F)F)C(F)(F)F
InChiKey:
CYSJNTQNMDWAJV-UHFFFAOYSA-N
InChi :
InChI=1S/C21H14F8N6O2/c22-12-4-2-1-3-11(12)9-35-16(14-5-6-37-34-14)7-15(33-35)18-30-8-13(23)17(32-18)31-10-19(36,20(24,25)26)21(27,28)29/h1-8,36H,9-10H2,(H,30,31,32)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Mepolizumab} MedChemExpress|{Mepolizumab} Interleukin Related|{Mepolizumab} Technical Information|{Mepolizumab} Data Sheet|{Mepolizumab} manufacturer|{Mepolizumab} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC50 of 197 nM.|Product information|CAS Number: 1628730-49-3|Molecular Weight: 534.36|Formula: C21H14F8N6O2|Chemical Name: 1,1,1-trifluoro-3-[(5-fluoro-2-{1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)-1H-pyrazol-3-yl}pyrimidin-4-yl)amino]-2-(trifluoromethyl)propan-2-ol|Smiles: OC(CNC1=NC(=NC=C1F)C1C=C(C2C=CON=2)N(CC2=CC=CC=C2F)N=1)(C(F)(F)F)C(F)(F)F|InChiKey: CYSJNTQNMDWAJV-UHFFFAOYSA-N|InChi: InChI=1S/C21H14F8N6O2/c22-12-4-2-1-3-11(12)9-35-16(14-5-6-37-34-14)7-15(33-35)18-30-8-13(23)17(32-18)31-10-19(36,20(24,25)26)21(27,28)29/h1-8,36H,9-10H2,(H,30,31,32)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 250 mg/mL (467.{{Mirvetuximab} MedChemExpress|{Mirvetuximab} Antifolate|{Mirvetuximab} Technical Information|{Mirvetuximab} Description|{Mirvetuximab} supplier|{Mirvetuximab} Epigenetics} 85 mM; Need ultrasonic).PMID:28038441 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|