Product Name :
Lusutrombopag
Description:
Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist, used for treatment of chronic liver disease.
CAS:
1110766-97-6
Molecular Weight:
591.55
Formula:
C29H32Cl2N2O5S
Chemical Name:
(2E)-3-{2,6-dichloro-4-[(4-{3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl}-1,3-thiazol-2-yl)carbamoyl]phenyl}-2-methylprop-2-enoic acid
Smiles :
C/C(=C\C1C(Cl)=CC(=CC=1Cl)C(=O)NC1=NC(=CS1)C1=CC=CC([C@H](C)OCCCCCC)=C1OC)/C(O)=O
InChiKey:
NOZIJMHMKORZBA-KJCUYJGMSA-N
InChi :
InChI=1S/C29H32Cl2N2O5S/c1-5-6-7-8-12-38-18(3)20-10-9-11-21(26(20)37-4)25-16-39-29(32-25)33-27(34)19-14-23(30)22(24(31)15-19)13-17(2)28(35)36/h9-11,13-16,18H,5-8,12H2,1-4H3,(H,35,36)(H,32,33,34)/b17-13+/t18-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist, used for treatment of chronic liver disease.|Product information|CAS Number: 1110766-97-6|Molecular Weight: 591.55|Formula: C29H32Cl2N2O5S|Chemical Name: (2E)-3-{2,6-dichloro-4-[(4-{3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl}-1,3-thiazol-2-yl)carbamoyl]phenyl}-2-methylprop-2-enoic acid|Smiles: C/C(=C\C1C(Cl)=CC(=CC=1Cl)C(=O)NC1=NC(=CS1)C1=CC=CC([C@H](C)OCCCCCC)=C1OC)/C(O)=O|InChiKey: NOZIJMHMKORZBA-KJCUYJGMSA-N|InChi: InChI=1S/C29H32Cl2N2O5S/c1-5-6-7-8-12-38-18(3)20-10-9-11-21(26(20)37-4)25-16-39-29(32-25)33-27(34)19-14-23(30)22(24(31)15-19)13-17(2)28(35)36/h9-11,13-16,18H,5-8,12H2,1-4H3,(H,35,36)(H,32,33,34)/b17-13+/t18-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 33 mg/mL (55.{{Anti-Mouse TNFR2 Antibody} web|{Anti-Mouse TNFR2 Antibody} Apoptosis|{Anti-Mouse TNFR2 Antibody} Purity & Documentation|{Anti-Mouse TNFR2 Antibody} Description|{Anti-Mouse TNFR2 Antibody} supplier|{Anti-Mouse TNFR2 Antibody} Cancer} 79 mM).{{Sitagliptin phosphate} MedChemExpress|{Sitagliptin phosphate} Metabolic Enzyme/Protease|{Sitagliptin phosphate} Technical Information|{Sitagliptin phosphate} In Vivo|{Sitagliptin phosphate} custom synthesis|{Sitagliptin phosphate} Epigenetic Reader Domain} |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:25955218 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Lusutrombopag acts selectively on the human TPO receptor and activates signal transduction pathways that promote the proliferation and differentiation of bone marrow cells into megakaryocytes, thereby increasing platelet levels.|Products are for research use only. Not for human use.|
