Product Name :
4-Imidazoleacetic acid HCl
Synonym :
Chemical Name :
CAS NO.:
3251-69-2
Molecular formula :
C5H6N2O2·HCl
Molecular Weight:
162.57 g/mol
Classification :
MedChemExpress Products > Research Chemicals > Building Blocks > Nitrogen Heterocycles > 4-Imidazoleacetic acid HCl
Description:
4-Imidazoleacetic acid HCl is a fluorescent probe that binds to the α1 subunit of the dinucleotide phosphate (NADH) oxidoreductase. It has been shown to inhibit mitochondrial functions, which may be due to its ability to inhibit the pentose phosphate pathway and reduce reactive oxygen species levels. 4-Imidazoleacetic acid HCl has also shown inhibitory properties against congestive heart failure by acting on the mitochondria and inhibiting energy metabolism. It can also be used as a chemical biology tool for studying protein interactions with NADH dehydrogenase. The x-ray crystal structures have revealed that 4-imidazoleacetic acid HCl binds to the active site of NADH oxidoreductase with an orientation that mimics a substrate molecule. This allows it to bind tightly and disrupt enzyme activity.
Purity :
>98%
Specifications :
10 mM * 1 mL
Price.:
88
Price unit :
$
Inventory :
In stock
Related websites: https://www.medchemexpress.com
61791-12-6 supplier 937174-76-0 Synonym PMID:30571052 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com
