**Background** Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the mammalian central nervous system, playing a critical role in regulating neuronal excitability. The $\text{GABA}_{\text{A}}$ receptor, a ligand-gated ion channel,…
**Background** Cancer remains one of the most challenging diseases to treat due to the heterogeneity of tumor phenotypes and the emergence of drug resistance. Ovarian cancer, in particular, is characterized…
**Background** B-cell malignancies, including mantle cell lymphoma (MCL) and diffuse large B-cell lymphoma (DLBCL), are characterized by the dysregulation of B-cell receptor (BCR) signaling. A central component of this signaling…
Pemphigoid gestationis (PG) is a severe autoimmune blistering disorder that typically arises during mid-to-late pregnancy and is associated with significant maternal morbidity and fetal risk, including preterm birth, intrauterine growth…
The environmental fate of cadmium (Cd²⁺) in calcite-rich soils is significantly influenced by the presence and composition of dissolved organic matter (DOM), which acts as a key modulator of metal…
The Telepass project reveals a critical challenge in modern healthcare: despite widespread access to curative treatments for hepatitis C virus (HCV), many patients remain undiagnosed or disconnected from care. In…
The surgical management of primary hyperparathyroidism (PHPT) has evolved significantly with the rise of minimally invasive parathyroidectomy, a technique that offers reduced morbidity, shorter recovery times, and improved patient satisfaction.…
A practical and scalable protocol for the synthesis of silyl ethers through photocatalytic dehydrogenative coupling of alcohols with hydrosilanes has been successfully demonstrated. The reaction, catalyzed by Ru(bpy)₃Cl₂ (0.5 mol%)…
A multifunctional thermoswitchable fluorescent system has been successfully developed through a synergistic dual-channel design based on fatty acid (FA)-mediated phase transitions, enabling reversible full-color emission with high contrast, tunable response…
The reliability of bacteriophage experiments hinges on the stability of phage suspensions during storage, mixing, and temperature exposure. However, a critical yet frequently overlooked variable is the type and quality…