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E. Part of his explanation for the error was his willingness to capitulate when tired: `I did not ask for any medical history or anything like that . . . over the phone at 3 or 4 o’clock [in the morning] you simply say yes to anything’ pnas.1602641113 Interviewee 25. Regardless of sharing these equivalent qualities, there have been some differences in error-producing conditions. With KBMs, medical doctors had been conscious of their information deficit at the time of your prescribing selection, in contrast to with RBMs, which led them to take among two pathways: strategy other people for314 / 78:2 / Br J Clin PharmacolLatent conditionsSteep hierarchical structures inside medical teams prevented physicians from searching for help or indeed getting adequate aid, highlighting the importance on the prevailing health-related culture. This varied in between specialities and accessing assistance from seniors appeared to be extra problematic for FY1 trainees working in surgical specialities. Interviewee 22, who worked on a surgical ward, described how, when he approached seniors for advice to prevent a KBM, he felt he was annoying them: `Q: What made you believe that you simply may be annoying them? A: Er, simply because they’d say, you understand, initial words’d be like, “Hi. Yeah, what’s it?” you realize, “I’ve scrubbed.” That’ll be like, kind of, the introduction, it wouldn’t be, you understand, “Any difficulties?” or something like that . . . it just doesn’t sound extremely approachable or friendly around the telephone, you realize. They just sound rather direct and, and that they were busy, I was inconveniencing them . . .’ Interviewee 22. Medical culture also influenced doctor’s behaviours as they acted in ways that they felt were essential so that you can fit in. When exploring doctors’ reasons for their KBMs they discussed how they had chosen not to seek assistance or info for fear of looking incompetent, in particular when new to a ward. Interviewee 2 below explained why he did not verify the dose of an IKK 16 antibiotic despite his uncertainty: `I knew I should’ve Hesperadin site looked it up cos I didn’t actually know it, but I, I believe I just convinced myself I knew it becauseExploring junior doctors’ prescribing mistakesI felt it was something that I should’ve known . . . since it is very simple to have caught up in, in getting, you realize, “Oh I am a Medical professional now, I know stuff,” and using the stress of folks that are maybe, sort of, a bit bit more senior than you thinking “what’s wrong with him?” ‘ Interviewee 2. This behaviour was described as subsiding with time, suggesting that it was their perception of culture that was the latent situation as opposed to the actual culture. This interviewee discussed how he at some point discovered that it was acceptable to verify information and facts when prescribing: `. . . I discover it fairly good when Consultants open the BNF up inside the ward rounds. And also you believe, properly I am not supposed to understand each and every single medication there’s, or the dose’ Interviewee 16. Health-related culture also played a role in RBMs, resulting from deference to seniority and unquestioningly following the (incorrect) orders of senior medical doctors or knowledgeable nursing staff. An excellent example of this was offered by a doctor who felt relieved when a senior colleague came to help, but then prescribed an antibiotic to which the patient was allergic, despite obtaining already noted the allergy: `. journal.pone.0169185 . . the Registrar came, reviewed him and said, “No, no we must give Tazocin, penicillin.” And, erm, by that stage I’d forgotten that he was penicillin allergic and I just wrote it on the chart without having thinking. I say wi.E. A part of his explanation for the error was his willingness to capitulate when tired: `I didn’t ask for any medical history or anything like that . . . over the telephone at 3 or four o’clock [in the morning] you just say yes to anything’ pnas.1602641113 Interviewee 25. Regardless of sharing these comparable qualities, there were some variations in error-producing situations. With KBMs, doctors were conscious of their information deficit in the time with the prescribing selection, as opposed to with RBMs, which led them to take certainly one of two pathways: method other individuals for314 / 78:2 / Br J Clin PharmacolLatent conditionsSteep hierarchical structures within healthcare teams prevented physicians from searching for enable or certainly receiving adequate assist, highlighting the value on the prevailing healthcare culture. This varied between specialities and accessing suggestions from seniors appeared to become extra problematic for FY1 trainees working in surgical specialities. Interviewee 22, who worked on a surgical ward, described how, when he approached seniors for suggestions to stop a KBM, he felt he was annoying them: `Q: What produced you believe that you just might be annoying them? A: Er, just because they’d say, you understand, very first words’d be like, “Hi. Yeah, what exactly is it?” you realize, “I’ve scrubbed.” That’ll be like, kind of, the introduction, it wouldn’t be, you realize, “Any challenges?” or something like that . . . it just doesn’t sound pretty approachable or friendly on the telephone, you know. They just sound rather direct and, and that they were busy, I was inconveniencing them . . .’ Interviewee 22. Medical culture also influenced doctor’s behaviours as they acted in methods that they felt had been vital to be able to fit in. When exploring doctors’ factors for their KBMs they discussed how they had selected to not seek advice or info for worry of looking incompetent, particularly when new to a ward. Interviewee 2 below explained why he did not check the dose of an antibiotic despite his uncertainty: `I knew I should’ve looked it up cos I didn’t really know it, but I, I feel I just convinced myself I knew it becauseExploring junior doctors’ prescribing mistakesI felt it was anything that I should’ve identified . . . because it is quite uncomplicated to have caught up in, in being, you know, “Oh I am a Physician now, I know stuff,” and with all the stress of individuals that are possibly, sort of, a little bit bit extra senior than you thinking “what’s wrong with him?” ‘ Interviewee two. This behaviour was described as subsiding with time, suggesting that it was their perception of culture that was the latent condition as an alternative to the actual culture. This interviewee discussed how he at some point learned that it was acceptable to check data when prescribing: `. . . I find it really nice when Consultants open the BNF up within the ward rounds. And also you believe, properly I’m not supposed to understand each single medication there is, or the dose’ Interviewee 16. Healthcare culture also played a role in RBMs, resulting from deference to seniority and unquestioningly following the (incorrect) orders of senior physicians or skilled nursing staff. A superb instance of this was given by a physician who felt relieved when a senior colleague came to help, but then prescribed an antibiotic to which the patient was allergic, regardless of having currently noted the allergy: `. journal.pone.0169185 . . the Registrar came, reviewed him and stated, “No, no we need to give Tazocin, penicillin.” And, erm, by that stage I’d forgotten that he was penicillin allergic and I just wrote it on the chart with out considering. I say wi.

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