Product Name: GPR88 Polyclonal Antibody, HRP Conjugated
Applications: WB, IHC-P
Reactivity: Human, Mouse, Rat
Conjugation: HRP
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human G protein coupled receptor 88
Clonality: Polyclonal
CAS NO: 59804-37-4
Product: K-115 (free base)
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
Synonyms: G protein coupled receptor 88; G protein-coupled receptor 88; G-protein coupled receptor 88; Probable G protein coupled receptor 88; STRG; Striatum specic G protein coupled receptor; GPR88_HUMAN; GPCR88.
Background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR88 (G protein-coupled receptor 88), also known as STRG, is a 384 amino acid multi-pass membrane protein that localizes to the cell membrane and belongs to the G protein coupled receptor family. Expressed exclusively in striatum, GPR88 functions as an orphan receptor that may be involved in signaling pathways throughout the cell. Human GPR88 shares 95% sequence identity with its rat counterpart, suggesting a conserved role between species.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22306067?dopt=Abstract
