Product Name: GRAMD3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: ALEXA FLUOR® 350
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human GRAMD3/NS3TP2
Clonality: Polyclonal
CAS NO: 31430-15-6
Product: PSN632408
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: FLJ21313; GRAM domain containing 3; GRAM domain-containing protein 3; GRAM domain-containing protein 3ï¼› GRAM3_HUMAN; Gramd3; HCV NS3-transactivated protein 2; hepatitis C virus nonstructural protein 3 transactivating protein 2; NS3TP2.
Background: GRAMD3 is a 432 amino acid protein that contains one GRAM domain and is encoded by a gene that maps to human chromosome 5q23.2. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26424557?dopt=Abstract
