Product Name: GRF2 Polyclonal Antibody , Biotin Conjugated
Applications: WB
Reactivity: Human, Mouse, Rat
Conjugation: Biotin
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human GRF2
Clonality: Polyclonal
CAS NO: 1355631-24-1
Product: (20S)-Protopanaxatriol
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: GRF2; RAS-GRF2; Ras-specific guanine nucleotide-releasing factor 2; Ras guanine nucleotide exchange factor 2; RASGRF2
Background: Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/28454319?dopt=Abstract
