Product Name: GRK4+5+6 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: ALEXA FLUOR® 488
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human GRK6
Clonality: Polyclonal
CAS NO: 82410-32-0
Product: Cyproterone (acetate)
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: GRK4: G protein-coupled receptor kinase 4, G protein-coupled receptor kinase GRK4, GPRK2L, GPRK4GRK5: G protein-coupled receptor kinase 5, G protein-coupled receptor kinase GRK5, GPRK5GRK6: G protein-coupled receptor kinase 6, G protein-coupled receptor kinase GRK6, GPRK6
Background: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their down-regulation.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20140201?dopt=Abstract
