Product Name: GRPP Polyclonal Antibody
Applications: IHC-P, IF(IHC-P)
Reactivity: Mouse, Rat
Conjugation: Unconjugated
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from rat GRPP
Clonality: Polyclonal
CAS NO: 115436-72-1
Product: Ethambutol
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Synonyms: glicentin-related polypeptide; GCG; Glicentin related polypeptide; Glucagon precursor; GRPP; Oxyntomodulin; OXM; OXY; GLUC_HUMAN.
Background: The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq].
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20357108?dopt=Abstract
