Product Name: GSK-3 Beta(Thr390) Polyclonal Antibody, Cy3 Conjugated
Applications: IF(IHC-P)
Reactivity: Human
Conjugation: Cy3
Host: Rabbit
Sourcr: KLH conjugated Synthesised phosphopeptide derived from human GSK-3 Beta around the phosphorylation site of Thr390
Clonality: Polyclonal
CAS NO: 1242156-23-5
Product: Doxapram
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: GSK3B(Thr390); GSK3B(T390); p-GSK-3 Beta(Thr390); p-GSK-3 beta(T390); Glycogen synthase kinase 3 beta; GSK 3 beta; GSK 3B; GSK3B; GSK3B protein; GSK3beta isoform; GSK3 beta; Glycogen synthase kinase-3 beta; GSK-3 beta; GSK3B_HUMAN.
Background: Glycogen synthase kinase 3 (GSK3) is a proline directed serine threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. GSK3 has been implicated in fundamental cell processes such as cell fate determination, metabolism, transcriptional control and oncogenesis. Two isoforms, alpha (GSK3A; OMIM 606784) and beta, show a high degree of amino acid homology within their catalytic domains. GSK3B is involved in energy metabolism, neuronal cell development and body pattern formation.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23940571?dopt=Abstract
