Product Name: Gasdermin like Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated
Applications: IF(IHC-P)
Reactivity: Human
Conjugation: ALEXA FLUOR® 488
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human GSDML/Gasdermin like
Clonality: Polyclonal
CAS NO: 1232416-25-9
Product: Trimethoprim
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: 123; 156; Gasdermin B; Gasdermin like protein; Gasdermin-B; Gasdermin-like protein; GSDMB; GSDMB_HUMAN; GSDML; PP4052; PRO2521.
Background: GSDML is a member of the GSDMDC (gasdermin-domain containing) family of proteins. Members of the GSDMDC family are involved in a wide variety of cellular processes, including cell-cycle control, extracellular matrix production, differentiation and apoptosis, and have been associated with the development and progression of cancer. GSDML is a widely expressed protein found in both cancerous and non-cancerous tissues localizing to the cytoplasm and in secretory vesicles. The gene encoding GSDML is thought to have been generated by a duplication event of the GSDM1 gene which encodes gasdermin. In addition, various isoforms exist for GSDML.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26758364?dopt=Abstract
