Product Name: HBS1L Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated
Applications: IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: ALEXA FLUOR® 555
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human HBS1L
Clonality: Polyclonal
CAS NO: 761438-38-4
Product: AZD2858
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: EF 1a; ERF3 similar protein; ERFS; HBS1; HBS1 like protein; HBS1L; Hsp70 subfamily B suppressor 1 like protein; KIAA1038; HBS1L_HUMAN.
Background: HBS1L is a 684 amino acid protein that belongs to the GTP-binding elongation factor family and exists as multiple alternatively spliced isoforms. Expressed in kidney, brain, heart, placenta, liver, muscle and pancreas, HSB1L is thought to play a role in controlling fetal hemoglobin levels, specifically influencing platelet, monocyte and erythrocyte hemoglobin content. The gene encoding HBS1L maps to a locus on human chromosome 6 that is associated with sickle cell anemia and β-thalassemia, suggesting a role for HBS1L in the pathogenesis of blood disorders.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19026396?dopt=Abstract
