Product Name: HERC2 Polyclonal Antibody, Cy5 Conjugated
Applications: IF(IHC-P)
Reactivity: Human
Conjugation: Cy5
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human HERC2
Clonality: Polyclonal
CAS NO: 287194-40-5
Product: OSI-420
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: HECT domain and RCC1 like domain containing protein 2; Hect domain and RLD 2; jdf2; p528; SHEP1; HERC2_HUMAN.
Background: HERC2 is a belongs to the HERC gene family that encodes a group of unusually large proteins, which contain multiple structural domains. All members have at least 1 copy of an N-terminal region showing homology to the cell cycle regulator RCC1 and a C-terminal HECT (homologous to E6-AP C terminus) domain found in a number of E3 ubiquitin protein ligases. Genetic variations in this gene are associated with skin/hair/eye pigmentation variability. Multiple pseudogenes of this gene are located on chromosomes 15 and 16.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27662285?dopt=Abstract
