Product Name: HERC3 Polyclonal Antibody, FITC Conjugated
Applications: IF(IHC-P)
Reactivity: Human
Conjugation: FITC
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human HERC3
Clonality: Polyclonal
CAS NO: 918504-65-1
Product: BMS-690514
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: HECT domain and RCC1 like domain containing protein 3; Hect domain and RLD 3; HERC 3; KIAA0032; Probable E3 ubiquitin protein ligase HERC3; HERC3_HUMAN.
Background: HERC3 is a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23691241?dopt=Abstract