Product Name: Heme Oxygenase Polyclonal Antibody, Biotin Conjugated
Applications: WB, IHC-P
Reactivity: Human, Mouse, Rat
Conjugation: Biotin
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from human Heme Oxygenase 1
Clonality: Polyclonal
CAS NO: 912445-05-7
Product: Rifabutin
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: HO-1; HSP32; HMOX1D; bK286B1; Heme oxygenase 1; HMOX1; HO; HO1
Background: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18296656?dopt=Abstract