Product Name: Heparin cofactor 2 (74E5) Monoclonal Antibody
Applications: WB
Reactivity: Human
Conjugation: Unconjugated
Host: Mouse
Sourcr: Protein purified from Human plasma
Clonality: Monoclonal
CAS NO: 202138-50-9
Product: PSI-6130
Isotype: IgG2b κ
Concentration: 1ug/ul
Purification: Purified by Protein G.
Storage: HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol. Store for 1 year at -20°C from date of shipment.
Synonyms: HC2; LS2; HCF2; HCII; HLS2; THPH10; D22S673; Heparin cofactor 2; Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2; Serpin D1; SERPIND1
Background: Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25077967?dopt=Abstract
