Product Name: Hepatitis C Virus NS4B Antibody, HRP Conjugated
Applications: WB, IHC-P
Reactivity: Virus
Conjugation: HRP
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from Hepatitis C Virus NS4B
Clonality: Polyclonal
CAS NO: 1195768-06-9
Product: PF-2545920
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
Synonyms: HCV; HCV NS4B; Non structural protein 4B; NS4B; p27.
Background: HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural protein necessary for viral replication. NS4B induces a specific membrane alteration that serves as a scaffold for the virus replication complex. This membrane alteration gives rise to the so-called ER-derived membranous web that contains the replication complex.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27775041?dopt=Abstract
