Product Name: Hepatitis C Virus RNA-directed RNA polymerase Antibody, Biotin Conjugated
Applications: WB, IHC-P
Reactivity: Virus
Conjugation: Biotin
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from Hepatitis C Virus RNA-directed RNA polymerase
Clonality: Polyclonal
CAS NO: 343787-29-1
Product: PF 03716556
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: RNA-directed RNA polymerase; p68; RNA dependent RNA polymerase.
Background: The RNA directed RNA polymerase is also known as non-structural protein NS5B. NS5B is a 65 kDa protein that resembles other viral RNA polymerases. Hepatitis C virus (HCV) replication is thought to occur in membrane bound replication complexes. These complexes transcribe the positive strand and the resulting minus strand is used as a template for the synthesis of genomic RNA. There are two viral proteins involved in the reaction, NS3 and NS5B
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24252623?dopt=Abstract
